June 2021 Data Release

We are pleased to release datasets from following T2D and T1D relevant publication:

• Large-scale genetic association and single cell accessible chromatin mapping defines cell type-specific mechanisms of type 1 diabetes risk

• Landscape of stimulation-responsive chromatin across diverse human immune cells

• Lineage-Specific Genome Architecture Links Enhancers and Non-coding Disease Variants to Target Gene Promoters

• Genetic Drivers of Epigenetic and Transcriptional Variation in Human Immune Cells

• The impact of proinflammatory cytokines on the β-cell regulatory landscape provides insights into the genetics of type 1 diabetes

• β-Glucan Reverses the Epigenetic State of LPS-Induced Immunological Tolerance

• Glutaminolysis and Fumarate Accumulation Integrate Immunometabolic and Epigenetic Programs in Trained Immunity

• CD8 + T Cells from Human Neonates Are Biased toward an Innate Immune Response

• An integrated multi-omics approach identifies the landscape of interferon-α-mediated responses of human pancreatic beta cells

• Genome-wide enhancer maps link risk variants to disease genes

• Defining human cardiac transcription factor hierarchies using integrated single-cell heterogeneity analysis

• Pancreatic progenitor epigenome maps prioritize type 2 diabetes risk genes with roles in development

• Population and Single-Cell Analysis of Human Cardiogenesis Reveals Unique LGR5 Ventricular Progenitors in Embryonic Outflow Tract

• A Single-Cell Transcriptomic Map of the Human and Mouse Pancreas Reveals Inter- and Intra-cell Population Structure

• Genome-wide analysis of PDX1 target genes in human pancreatic progenitors