Search – Common Metabolic Diseases Genome Atlas

Showing 11 of 11 results

Publication
released
Genome-wide analysis of the interplay between chromatin-associated RNA and 3D genome organization in human cells
Riccardo Calandrelli, Xingzhao We, John Lalith Charles Richard, et al.
Nat Commun. 2023-10-16;14(1):6519.
Available supplemental data: website
URL: https://data.4dnucleome.org
Data summary: All high-throughput data supporting the current study have been deposited on the 4D Nucleome Data…
Available supplemental data: website
URL: https://github.com/Zhong-Lab-UCSD/RNA3Dgenome-code-repository
Data summary: The codes used for the analysis have been deposited and made publicly available on GitHub at…
Publication
released
Increased body mass index is linked to systemic inflammation through altered chromatin co-accessibility in human preadipocytes
Kristina M. Garske, Asha Kar, Caroline Comenho, et al.
Nat Commun. 2023-07-14;14(1):4214.
Publication
released
Cis-regulatory architecture of human ESC-derived hypothalamic neuron differentiation aids in variant-to-gene mapping of relevant complex traits
Matthew C. Pahl, Claudia A. Doege, Kenyaita M. Hodge, et al.
Nat Commun. 2021-11-19;12(1):6749.
Publication
released
Functional characterization of T2D-associated SNP effects on baseline and ER stress-responsive β cell transcriptional activation
Shubham Khetan, Susan Kales, Romy Kursawe, et al.
Nat Commun. 2021-09-02;12(1):5242.
URL: https://cmdga.org/publications/63f879cd-f426-4495-a12d-103fdac5867c/
URL: https://zenodo.org/record/4974390#.YzHqHi-B39A
Data summary: Linked to Zenodo
Publication
released
Joint disease-specificity at the regulatory base-pair level
Pushpanathan Muthuirulan, Dewei Zhao, Mariel Young, et al.
Nat Commun. 2021-07-06;12(1):4161.
Publication
released
Common schizophrenia risk variants are enriched in open chromatin regions of human glutamatergic neurons
Mads E. Hauberg, Jordi Creus-Muncunill, Jaroslav Bendl, et al.
Nat Commun. 2020-11-04;11(1):5581.
Publication
released
Genetic variant effects on gene expression in human pancreatic islets and their implications for T2D
Ana Viñuela, Arushi Varshney, Martijn van de Bunt, et al.
Nat Commun. 2020-09-30;11(1):4912.
URL: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7528108/
Publication
released
Regulatory sites for splicing in human basal ganglia are enriched for disease-relevant information
Sebastian Guelfi, Karishma D’Sa, Juan A. Botía, et al.
Nat Commun. 2020-02-25;11(1):1041.
Publication
released
Functional testing of thousands of osteoarthritis-associated variants for regulatory activity
Jason C Klein, Aidan Keith, Sarah J Rice, et al.
Nat Commun. 2019-06-04;10(1):2434.
Publication
released
ATAC-Seq analysis reveals a widespread decrease of chromatin accessibility in age-related macular degeneration
Jie Wang, Cristina Zibetti, Peng Shang, et al.
Nat Commun. 2018-04-10;9(1):1364.
Publication
released
Re-analysis of public genetic data reveals a rare X-chromosomal variant associated with type 2 diabetes
Sílvia Bonàs-Guarch, Marta Guindo-Martínez, Irene Miguel-Escalada, et al.
Nat Commun. 2018-01-22;9(1):321.