Showing 9 of 9 results

• Publication

  released

  Identification of target genes and regulatory networks for bone mineral density GWAS loci through systematic targeting and inhibition

  Mohammadjavad Kahlani, Larry Mesner, Vedavathi Madhu, et al.

  bioRxiv. 2026-02-16;(Preprint)

  • PMID:41757073
  • PMCID:PMC12934652
  • doi:10.64898/2026.02.11.705362

• Publication

  released

  Response splicing QTLs in primary human chondrocytes identifies putative osteoarthritis risk genes

  Seyoun Byun, Philip Coryell, Nicole Kramer, et al.

  bioRxiv. 2024-11-12;

  • doi:10.1101/2024.11.11.622754

• Publication

  released

  Population-scale skeletal muscle single-nucleus multi-omic profiling reveals extensive context specific genetic regulation

  Arushi Varshney Arushi Varshney, Nandini Manickam, Peter Orchard, et al.

  bioRxiv. 2023-12-15;

  • PMID:38168419
  • PMCID:PMC10760134
  • doi:10.1101/2023.12.15.571696

  URL: https://www.biorxiv.org/content/10.1101/2023.12.15.571696v2

• Publication

  released

  Single-cell gene expression and chromatin accessibility profiling of human pancreatic islets at basal and stimulatory conditions nominates mechanisms of type 1 diabetes genetic risk

  Ricardo D’Oliveira Albanus, Xuming Tang, Henry J. Taylor, et al.

  bioRxiv. 2022-11-14;

  • doi:10.1101/2022.11.12.516291

• Publication

  released

  Cryomilling Tethered Chromatin Conformation Capture reveal new insights into inter-chromosomal interactions

  Jiang Xu, Sanjeev Kumar, Nan Hua, et al.

  bioRxiv. 2022-02-12;

  • doi:10.1101/2022.02.03.478915

• Publication

  released

  Fine-mapping, trans-ancestral and genomic analyses identify causal variants, cells, genes and drug targets for type 1 diabetes

  C.C. Robertson, J.R.J. Inshaw, S. Onengut-Gumuscu, et al.

  bioRxiv. 2020-06-20;

  • doi:10.1101/2020.06.19.158071

• Publication

  released

  The three-dimensional chromatin structure of the major human pancreatic cell types reveals lineage-specific regulatory architecture of T2D risk

  Chun Su, Long Gao, Catherine L. May, et al.

  bioRxiv.

  • doi:10.1101/2021.11.30.470653

• Publication

  released

  Mapping genetic effects on cell type-specific chromatin accessibility and annotating complex trait variants using single nucleus ATAC-seq

  Paola Benaglio, Jacklyn Newsome, Jee Yun Han, et al.

  bioRxiv.

  • doi:10.1101/2020.12.03.387894

• Publication

  released

  Mapping the genetic architecture of human traits to cell types in the kidney identifies mechanisms of disease and potential treatments

  Xin Sheng, Ziyuan Ma, Junnan Wu, et al.

  bioRxiv.

  • doi:10.1101/2020.11.09.375592