Showing 13 of 13 results

• Publication

  released

  An integrated map of cell type-specific gene expression in pancreatic islets

  Ruth M Elgamal, Parul Kudtarkar, Rebecca L Melton, et al.

  Diabetes. 2023-15-08;(db230130)

  • PMID:37582230
  • doi:10.2337/db23-0130

• Publication

  released

  A Transcription Start Site Map in Human Pancreatic Islets Reveals Functional Regulatory Signatures

  Arushi Varshney, Yasuhiro Kyono, Venkateswaran Ramamoorthi Elangovan, et al.

  Diabetes. 2021-04-13;(db201087)

  • doi:10.2337/db20-1087
  • PMID:33849996

• Publication

  released

  Identification and Massively Parallel Characterization of Regulatory Elements Driving Neural Induction

  Fumitaka Inoue, Anat Kreimer, Tal Ashuach, et al.

  Cell Stem Cell. 2019-11-07;25(5):713-727.e10.

  • PMID:31631012
  • PMCID:PMC6850896
  • doi:10.1016/j.stem.2019.09.010

• Publication

  released

  Type 2 Diabetes–Associated Genetic Variants Regulate Chromatin Accessibility in Human Islets

  Shubham Khetan, Romy Kursawe, Ahrim Youn, et al.

  Diabetes. 2018-11-01;67:2466–2477.

  • doi:10.2337/db18-0393
  • PMID:30181159

  URL: https://diabetes.diabetesjournals.org/content/67/11/2466

• Publication

  released

  Single-Cell Transcriptomic Analysis of Cardiac Differentiation from Human PSCs Reveals HOPX-Dependent Cardiomyocyte Maturation

  Clayton E Friedman, Quan Nguyen, Samuel W Lukowski, et al.

  Cell Stem Cell. 2018-10-04;23(4):586-598.e8.

  • doi:10.1016/j.stem.2018.09.009
  • PMID:30290179
  • PMCID:PMC6220122

• Publication

  released

  Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells

  Tahsin Stefan Barakat, Florian Halbritter, Man Zhang, et al.

  Cell Stem Cell. 2018-08-02;23(2):276-288.e8.

  • doi:10.1016/j.stem.2018.06.014
  • PMID:30033119
  • PMCID:PMC6084406

• Publication

  released

  Glucose-Induced Changes in Gene Expression in Human Pancreatic Islets: Causes or Consequences of Chronic Hyperglycemia

  Emilia Ottosson-Laakso, Ulrika Krus, Petter Storm, et al.

  Diabetes. 2017-12-01;66(12):3013-3028.

  • doi:10.2337/db17-0311
  • PMID:28882899

• Publication

  released

  A Loss-of-Function Splice Acceptor Variant in IGF2 Is Protective for Type 2 Diabetes

  Josep M Mercader, Rachel G Liao, Avery D Bell, et al.

  Diabetes. 2017-08-24;66(11):2903-2914.

  • doi:10.2337/db17-0187
  • PMID:28838971
  • PMCID:PMC5652606

• Publication

  released

  Large, Diverse Population Cohorts of hiPSCs and Derived Hepatocyte-like Cells Reveal Functional Genetic Variation at Blood Lipid-Associated Loci

  Evanthia E Pashos, YoSon Park, Xiao Wang, et al.

  Cell Stem Cell. 2017-04-06;20(4):558-570.e10.

  • doi:10.1016/j.stem.2017.03.017
  • PMID:28388432
  • PMCID:PMC5476422

• Publication

  released

  Single-Cell Transcriptomics of the Human Endocrine Pancreas

  Yue J. Wang, Jonathan Schug, Kyoung-Jae Won, et al.

  Diabetes. 2016-10-01;65(10):3028-38.

  • doi:10.2337/db16-0405
  • PMID:27364731

• Publication

  released

  Epigenetic Priming Of Enhancers Predicts Developmental Competence Of hESC-derived Endodermal Lineage Intermediates

  Allen Wang, Feng Yue, Yan Li, et al.

  Cell Stem Cell. 2015-04-02;16(4):386-399.

  • doi:10.1016/j.stem.2015.02.013
  • PMID:25842977

• Publication

  released

  Dynamic Chromatin Remodeling Mediated by Polycomb Proteins Orchestrates Pancreatic Differentiation of Human Embryonic Stem Cells

  Ruiyu Xie, Logan J. Everett, Hee-Woong Lim, et al.

  Cell Stem Cell. 2013-02-07;12(2):224-237.

  • doi:10.1016/j.stem.2012.11.023
  • PMID:23318056

• Publication

  released

  A Whole-Genome RNA Interference Screen Reveals a Role for Spry2 in Insulin Transcription and the Unfolded Protein Response

  Zachary Pappalardo, Deeksha Gambhir Chopra, Thomas G Hennings, et al.

  Diabetes. 2017-02-28;66(6):1703-1712.

  • doi:10.2337/db16-0962
  • PMID:28246293
  • PMCID:PMC5440024