Showing 10 of 10 results

• Publication

  released

  Characterizing cis-regulatory elements using single-cell epigenomics

  Sebastian Preissl, Kyle J Gaulton, Bing Ren.

  Nat Rev Genet. 2022-07-15;

  • doi:10.1038/s41576-022-00509-1
  • PMID:35840754

• Publication

  released

  Cis-regulatory architecture of human ESC-derived hypothalamic neuron differentiation aids in variant-to-gene mapping of relevant complex traits

  Matthew C. Pahl, Claudia A. Doege, Kenyaita M. Hodge, et al.

  Nat Commun. 2021-11-19;12(1):6749.

  • doi:10.1038/s41467-021-27001-4
  • PMID:34799566
  • PMCID:PMC8604959

• Publication

  released

  Functional characterization of T2D-associated SNP effects on baseline and ER stress-responsive β cell transcriptional activation

  Shubham Khetan, Susan Kales, Romy Kursawe, et al.

  Nat Commun. 2021-09-02;12(1):5242.

  • doi:10.1038/s41467-021-25514-6
  • PMID:34475398
  • PMCID:PMC8413311

  URL: https://cmdga.org/publications/63f879cd-f426-4495-a12d-103fdac5867c/

  URL: https://zenodo.org/record/4974390#.YzHqHi-B39A

  Data summary: Linked to Zenodo

• Publication

  released

  Joint disease-specificity at the regulatory base-pair level

  Pushpanathan Muthuirulan, Dewei Zhao, Mariel Young, et al.

  Nat Commun. 2021-07-06;12(1):4161.

  • doi:10.1038/s41467-021-24345-9
  • PMID:34230488
  • PMCID:PMC8260791

• Publication

  released

  Common schizophrenia risk variants are enriched in open chromatin regions of human glutamatergic neurons

  Mads E. Hauberg, Jordi Creus-Muncunill, Jaroslav Bendl, et al.

  Nat Commun. 2020-11-04;11(1):5581.

  • doi:10.1038/s41467-020-19319-2
  • PMID:33149216
  • PMCID:PMC7643171

• Publication

  released

  Genetic variant effects on gene expression in human pancreatic islets and their implications for T2D

  Ana Viñuela, Arushi Varshney, Martijn van de Bunt, et al.

  Nat Commun. 2020-09-30;11(1):4912.

  • doi:10.1038/s41467-020-18581-8
  • PMID:32999275
  • PMCID:PMC7528108

  URL: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7528108/

• Publication

  released

  Regulatory sites for splicing in human basal ganglia are enriched for disease-relevant information

  Sebastian Guelfi, Karishma D’Sa, Juan A. Botía, et al.

  Nat Commun. 2020-02-25;11(1):1041.

  • doi:10.1038/s41467-020-14483-x
  • PMID:32098967
  • PMCID:PMC7042265

• Publication

  released

  Functional testing of thousands of osteoarthritis-associated variants for regulatory activity

  Jason C Klein, Aidan Keith, Sarah J Rice, et al.

  Nat Commun. 2019-06-04;10(1):2434.

  • doi:10.1038/s41467-019-10439-y
  • PMID:31164647
  • PMCID:PMC6547687

• Publication

  released

  ATAC-Seq analysis reveals a widespread decrease of chromatin accessibility in age-related macular degeneration

  Jie Wang, Cristina Zibetti, Peng Shang, et al.

  Nat Commun. 2018-04-10;9(1):1364.

  • doi:10.1038/s41467-018-03856-y
  • PMID:29636475
  • PMCID:PMC5893535

• Publication

  released

  Re-analysis of public genetic data reveals a rare X-chromosomal variant associated with type 2 diabetes

  Sílvia Bonàs-Guarch, Marta Guindo-Martínez, Irene Miguel-Escalada, et al.

  Nat Commun. 2018-01-22;9(1):321.

  • doi:10.1038/s41467-017-02380-9
  • PMID:29358691
  • PMCID:PMC5778074