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Clear Filters
Perturbation type
  • 9CRISPR deletion
  • 7siRNA
  • 1CRISPR base editing
Perturbation throughput
  • 10single gene
  • 5arrayed
  • 2genome-wide pooled
Available data
  • 2tsv
File set status
  • 17released
Organism
  • 16Homo sapiens
  • 1Danio rario
Target(s) of assay
  • 1other context
Target(s) of assay
  • 1Insulin (Cell Signaling (C27C9) Rabbit mAb #3014)
Biosample type
  • 14cell line
  • 2stem cell model
  • 1whole organisms
Biosample term
  • 14EndoC-BH1
  • 2SB Ad3.1
  • 1Whole organism (Danio rario)
Tissue term
  • 13Pancreas
  • 2embryonic tissue
  • 1Zebrafish
  • 1pancreas
Date released
  • 10March, 2023
  • 6July, 2021
  • 1February, 2023
Software used
  • 2mageck
Lab
  • 10Anna Gloyn, Oxford
  • 6AMP-T2D consortium
  • 1Kyle Gaulton, UCSD
Project
  • 10community
  • 6AMP
  • 1T1D
RFA
  • 10community
  • 6AMP
  • 1T1D
type!!!!
  • Perturbation

Showing 7 of 17 results

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  • FileSet

    DSR160QHT

    released

    Gene Perturbation file set: CRISPR editing of RREB1 alleles in SB Ad3.1 stem cell model
    Lab: Anna Gloyn, Oxford
    Project: community
  • FileSet

    DSR716PDN

    released

    Gene Perturbation file set: CRISPR knockout of RREB1 in SB Ad3.1 stem cell model
    Lab: Anna Gloyn, Oxford
    Project: community
  • FileSet

    DSR997MQA

    released

    Gene Perturbation file set: CRISPR knockout of RREB1 expression in glucose-stimulated EndoC-BH1 cells after forskolin treatment (1 mmol/L glucose, 10 umol/L forskolin)
    Lab: Anna Gloyn, Oxford
    Project: community
  • FileSet

    DSR432EEC

    released

    Gene Perturbation file set: Knockdown of RREB1 expression in glucose-stimulated EndoC-BH1 cells (16.7 mmol/L glucose)
    Lab: Anna Gloyn, Oxford
    Project: community
  • FileSet

    DSR762ONN

    released

    Gene Perturbation file set: Candidate gene screen for beta cell function using siRNA in EndoC-Bh1, IBMX (100 μmol/L)
    Lab: AMP-T2D consortium
    Project: AMP
  • FileSet

    DSR878IPG

    released

    Gene Perturbation file set: Candidate gene screen for beta cell function using siRNA in EndoC-Bh1, tolbutamide (100 μmol/L)
    Lab: AMP-T2D consortium
    Project: AMP
  • FileSet

    DSR692EGA

    released

    Gene Perturbation file set: Genome-wide pooled CRISPR LoF screen for insulin content in EndoC-Bh1
    Lab: AMP-T2D consortium
    Project: AMP
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